Short Communication SOLID STATE FERMENTATION OF RICE CHAFF AS SUBSTRATE (VARIETY: DEVAMALLIGE) FOR FIBRINOLYTIC ENZYME PRODUCTION BY PENICILLIUMCHRYSOGENUM AGSF16
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چکیده
Rice chaff (Variety: Devamallige) is used as the substrate for the production of fibrinolytic enzyme by Penicilliumchrysogenum AGSF16 in solid state fermentation. The optimized moisture content of the medium is 35-45 %( v/w) an inoculumof 5-10% (v/v) and an average particle size of 400μm of the substrate were optimum for productivity and enzyme activity of 65-70 IU per ml filtrate was achieved after 96 hours of fermentation.The enzyme exhibited similar fibrinolytic activity as that of streptokinase on fibrin plates that were devoid of plasminogensuggesting that its fibrinolytic action is independent of plasminogen and it is not a plasminogen activator.
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